Nothing special on my end.
All music ripped to FLAC and played via Foobar through the MSI Gaming 5's onboard audio (with a power boost thing via molex). That in turn is connected to a SONY H-Fi I bought in 2007 that has always sounded good to me so I never bothered changing it.
Night time when the kids and partner are asleep I'll just exclusively use my ATH M-50 headphones which I find to be more than adequate. :0
LP setup is a Debut Carbon and a pair of Wharfedales but that's had to be put in storage for the time being. I prefer doing things digitally and I didn't consider the setup good enough to attempt any rips. Before that I had a USB turntable but let's not speak about that.
I should probably look into improving the PC audio setup as it's my main go to, but the layout of the room is a bit odd and I'm not too sure how I'd position things? From where I'm sitting both L & R speakers are to the right of me!